Interleukin 17a Antikörper (N-Term)

Produktnummer ABIN2787948

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Interleukin 17a in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Rind (Kuh), Schwein, Hund, Ziege, Pferd und Kaninchen.

Kurzübersicht für Interleukin 17a Antikörper (N-Term) (ABIN2787948)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reaktivität: Human, Ratte, Rind (Kuh), Schwein, Hund, Ziege, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Interleukin 17a Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Interleukin 17a Antikörper

Bindungsspezifität: N-Term

Sequenz: MTPGKTSLVS LLLLLSLEAI VKAGITIPRN PGCPNSEDKN FPRTVMVNLN

Homologie: Cow: 83%, Dog: 85%, Goat: 83%, Horse: 77%, Human: 100%, Pig: 83%, Rabbit: 92%, Rat: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against IL17A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL17A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 155 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: IL17A

Hintergrund: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Alias Symbols: CTLA8, IL-17, IL-17A, IL17
Protein Interaction Partner: DPH2, TRAF3IP2, TRAF6, IL17RA, IL17A,
Protein Size: 155

Molekulargewicht: 15 kDa

Gen-ID: 3605

NCBI Accession: NM_002190, NP_002181

UniProt: Q16552