Selectin E/CD62e Antikörper (N-Term)

Produktnummer ABIN2787940

Produktdetails anti-Selectin E/CD62e Antikörper

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Schaf, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Selectin E/CD62e Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK DVGMWNDERC

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SELE. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SELE

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 610 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Selectin E/CD62e

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Andere Bezeichnung: SELE (SELE Produkte)

Synonyme: SELE antikoerper, CD62E antikoerper, ELAM antikoerper, ELAM1 antikoerper, ESEL antikoerper, LECAM2 antikoerper, E-selectin antikoerper, Elam antikoerper, selectin E antikoerper, selectin, endothelial cell antikoerper, SELE antikoerper, Sele antikoerper

Hintergrund: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Alias Symbols: CD62E, ELAM, ELAM1, ESEL, LECAM2
Protein Interaction Partner: LGALS3BP, SELL, SERPING1, PXN, PTK2, GLG1, SELPLG, FLNA, VCL, PTPN11, PLCG1, CD44, ACTN2, TLN1,
Protein Size: 610

Molekulargewicht: 64 kDa

Gen-ID: 6401

NCBI Accession: NM_000450, NP_000441

UniProt: P16581

Pathways: Thromboxane A2 Receptor Signaling