CD4 Antikörper (C-Term)

Produktnummer ABIN2787938

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CD4 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Ziege und Pferd.

Kurzübersicht für CD4 Antikörper (C-Term) (ABIN2787938)

Target: CD4

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Ziege, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD4 Antikörper

Bindungsspezifität: C-Term

Sequenz: VLGGVAGLLL FIGLGIFFCV RCRHRRRQAE RMSQIKRLLS EKKTCQCPHR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CD4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 458 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Hintergrund: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alias Symbols: CD4mut
Protein Interaction Partner: env, RANBP9, vpu, ADRB2, UBC, CXCR4, UBL7, ABCB1, INPPL1, VCP, HGS, LCK, NR3C1, STUB1, TUBB, MYL12A, DHRS2, LRPPRC, FARSB, EIF3I, EIF3D, EIF3C, EIF3B, VIM, VDAC3, VDAC2, VDAC1, SSRP1, RPS19, RPS12, RPS10, RPS9, RPLP1, RPLP0, RPL22, RPL18, RPL7, PHB, NPM1,
Protein Size: 458

Molekulargewicht: 48 kDa

Gen-ID: 920

NCBI Accession: NM_000616, NP_000607

UniProt: P01730

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events