CD4 Antikörper (C-Term)

Produktnummer ABIN2787938

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD4 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Ziege und Pferd.

Kurzübersicht für CD4 Antikörper (C-Term) (ABIN2787938)

Target: CD4

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Ziege, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD4 Antikörper

Bindungsspezifität: C-Term

Sequenz: VLGGVAGLLL FIGLGIFFCV RCRHRRRQAE RMSQIKRLLS EKKTCQCPHR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CD4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 458 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Hintergrund: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alias Symbols: CD4mut
Protein Interaction Partner: env, RANBP9, vpu, ADRB2, UBC, CXCR4, UBL7, ABCB1, INPPL1, VCP, HGS, LCK, NR3C1, STUB1, TUBB, MYL12A, DHRS2, LRPPRC, FARSB, EIF3I, EIF3D, EIF3C, EIF3B, VIM, VDAC3, VDAC2, VDAC1, SSRP1, RPS19, RPS12, RPS10, RPS9, RPLP1, RPLP0, RPL22, RPL18, RPL7, PHB, NPM1,
Protein Size: 458

Molekulargewicht: 48 kDa

Gen-ID: 920

NCBI Accession: NM_000616, NP_000607

UniProt: P01730

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events