APP Antikörper (C-Term)

Produktnummer ABIN2787850

Der Kaninchen Polyklonal Anti-APP-Antikörper wurde für WB validiert. Er ist geeignet, APP in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für APP Antikörper (C-Term) (ABIN2787850)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-APP Antikörper

Bindungsspezifität: C-Term

Sequenz: LVMLKKKQYT SIHHGVVEVD AAVTPEERHL SKMQQNGYEN PTYKFFEQMQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against App. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human App

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 751 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Andere Bezeichnung: App

Hintergrund: App functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is involved in cell mobility and transcription regulation through protein-protein interactions.
Alias Symbols: Abeta, Abpp, Adap, Ag, betaApp, Cvap, E030013M08Rik
Protein Interaction Partner: Ranbp9, Cpeb1, Bace1, Snca, Prnp, Gga1, Stub1, Ubc, Kif1a, Mme, Mapk8ip2, Mapk8ip1, Dab1,
Protein Size: 751

Molekulargewicht: 83 kDa

Gen-ID: 11820

NCBI Accession: NM_001198824, NP_001185753

UniProt: P12023

Pathways: Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour