EIF2C3 Antikörper (N-Term)

Produktnummer ABIN2787838

Produktdetails anti-EIF2C3 Antikörper

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Zebrafisch (Danio rerio), Ratte, Hund, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2C3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MCEVLDIHNI DEQPRPLTDS HRVKFTKEIK GLKVEVTHCG TMRRKYRVCN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF2C3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2C3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 626 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF2C3

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Andere Bezeichnung: EIF2C3 (EIF2C3 Produkte)

Hintergrund: EIF2C3 is a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is
Alias Symbols: AGO3, FLJ12765, MGC86946, EIF2C3
Protein Interaction Partner: AGO4, TNRC6C, TNRC6A, AGO2, AGO1, ZNF346, DICER1, TNRC6B, TARBP2, PRKAR1A, ATP6V0D2, UBC, SLC22A2, BDNF, ATP4B, CAND1, CUL3, CUL5, AGO3, ATAD3B, WDR77, PSPC1, QPCTL, OTUD4, SF3B6, EIF3L, PRPF31, SUN2, PHB2, STK38, SPIN1, RUVBL2, IPO8, TAB1, PRMT5, TUBB4B,
Protein Size: 626

Molekulargewicht: 69 kDa

Gen-ID: 192669

NCBI Accession: NM_177422, NP_803171

UniProt: B1ALI0

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signalübertragung