ALDH1A1 Antikörper (Middle Region)

Produktnummer ABIN2787809

Produktdetails anti-ALDH1A1 Antikörper

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Schaf, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SVERAKKYIL GNPLTPGVTQ GPQIDKEQYD KILDLIESGK KEGAKLECGG

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%, Sheep: 93%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against ALDH1A1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALDH1A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 501 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Andere Bezeichnung: ALDH1A1 (ALDH1A1 Produkte)

Synonyme: ALDC antikoerper, ALDH-E1 antikoerper, ALDH1 antikoerper, ALDH11 antikoerper, PUMB1 antikoerper, RALDH1 antikoerper, AL1A1 antikoerper, aldc antikoerper, aldh-e1 antikoerper, aldh1 antikoerper, aldh11 antikoerper, pumb1 antikoerper, raldh1 antikoerper, GGADHR antikoerper, ALDH1A1 antikoerper, ALDDH antikoerper, Ahd2 antikoerper, Aldh1 antikoerper, Aldh2 antikoerper, Ahd-2 antikoerper, Aldh1a2 antikoerper, E1 antikoerper, Raldh1 antikoerper, Aldh1a1 antikoerper, ALHDII antikoerper, RALDH 1 antikoerper, RalDH1 antikoerper, aldehyde dehydrogenase 1 family member A1 antikoerper, aldehyde dehydrogenase 1 family, member A1 antikoerper, aldehyde dehydrogenase 1 family member A1 L homeolog antikoerper, aldehyde dehydrogenase family 1, subfamily A1 antikoerper, aldehyde dehydrogenase antikoerper, retinal dehydrogenase 1 antikoerper, ALDH1A1 antikoerper, aldh1a1 antikoerper, Aldh1a1 antikoerper, aldh1a1.L antikoerper, aldH1 antikoerper, LOC100732581 antikoerper, LOC101822890 antikoerper

Hintergrund: This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
Alias Symbols: ALDC, ALDH-E1, ALDH1, ALDH11, MGC2318, PUMB1, RALDH1
Protein Interaction Partner: ALDH1A1, SUMO1, NEDD8, NUPR1, POT1, NOS2, ALDH2, UBC,
Protein Size: 501

Molekulargewicht: 55 kDa

Gen-ID: 216

NCBI Accession: NM_000689, NP_000680

UniProt: P00352

Pathways: Dopaminergic Neurogenesis