ALDH1A1 Antikörper (Middle Region)

Produktnummer ABIN2787809

Der Kaninchen Polyklonal Anti-ALDH1A1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ALDH1A1 in Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Schaf, Meerschweinchen und Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für ALDH1A1 Antikörper (Middle Region) (ABIN2787809)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Schaf, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ALDH1A1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: SVERAKKYIL GNPLTPGVTQ GPQIDKEQYD KILDLIESGK KEGAKLECGG

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%, Sheep: 93%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against ALDH1A1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALDH1A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 501 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Andere Bezeichnung: ALDH1A1

Hintergrund: This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
Alias Symbols: ALDC, ALDH-E1, ALDH1, ALDH11, MGC2318, PUMB1, RALDH1
Protein Interaction Partner: ALDH1A1, SUMO1, NEDD8, NUPR1, POT1, NOS2, ALDH2, UBC,
Protein Size: 501

Molekulargewicht: 55 kDa

Gen-ID: 216

NCBI Accession: NM_000689, NP_000680

UniProt: P00352

Pathways: Dopaminergic Neurogenesis