ERP44 Antikörper (Middle Region)

Produktnummer ABIN2787804

Produktdetails anti-ERP44 Antikörper

Target: ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERP44 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LHREFHHGPD PTDTAPGEQA QDVASSPPES SFQKLAPSEY RYTLLRDRDE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TXNDC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TXNDC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 406 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ERP44

Target: ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

Andere Bezeichnung: TXNDC4 (ERP44 Produkte)

Synonyme: PDIA10 antikoerper, TXNDC4 antikoerper, 1110001E24Rik antikoerper, AI849526 antikoerper, AL033348 antikoerper, Txndc4 antikoerper, BWK4 antikoerper, txndc4 antikoerper, zgc:77883 antikoerper, endoplasmic reticulum protein 44 antikoerper, ERP44 antikoerper, Erp44 antikoerper, erp44 antikoerper

Hintergrund: TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Alias Symbols: ERP44, KIAA0573, PDIA10, TXNDC4
Protein Interaction Partner: FUS, UBC, SUMO1, NEDD8, NUDCD1, UBFD1, OSGEP, LARS, ISOC1, PLD3, PDCD10, FERMT2, YWHAZ, VCL, PFAS, PAK2, G6PD, FHL2, CNN2, TBCB, CKB, env, ELAVL1, SUMO4, RASSF5, USP32, USP46, UIMC1, ERO1LB, ERO1L, ITPR1, CD40,
Protein Size: 406

Molekulargewicht: 45 kDa

Gen-ID: 23071

NCBI Accession: NM_015051, NP_055866

UniProt: Q9BS26

Pathways: Cell RedoxHomeostasis, SARS-CoV-2 Protein Interaktom