ERP44 Antikörper (Middle Region)

Produktnummer ABIN2787804

Der Kaninchen Polyklonal Anti-ERP44-Antikörper wurde für WB validiert. Er ist geeignet, ERP44 in Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für ERP44 Antikörper (Middle Region) (ABIN2787804)

Target: ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERP44 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ERP44 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LHREFHHGPD PTDTAPGEQA QDVASSPPES SFQKLAPSEY RYTLLRDRDE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TXNDC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TXNDC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 406 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ERP44

Target: ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

Andere Bezeichnung: TXNDC4

Hintergrund: TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Alias Symbols: ERP44, KIAA0573, PDIA10, TXNDC4
Protein Interaction Partner: FUS, UBC, SUMO1, NEDD8, NUDCD1, UBFD1, OSGEP, LARS, ISOC1, PLD3, PDCD10, FERMT2, YWHAZ, VCL, PFAS, PAK2, G6PD, FHL2, CNN2, TBCB, CKB, env, ELAVL1, SUMO4, RASSF5, USP32, USP46, UIMC1, ERO1LB, ERO1L, ITPR1, CD40,
Protein Size: 406

Molekulargewicht: 45 kDa

Gen-ID: 23071

NCBI Accession: NM_015051, NP_055866

UniProt: Q9BS26

Pathways: Cell RedoxHomeostasis, SARS-CoV-2 Protein Interaktom