CAPZA3 Antikörper (N-Term)

Produktnummer ABIN2787761

Der Kaninchen Polyklonal anti-CAPZA3 Antikörper wird verwendet zum Nachweis von CAPZA3 in Proben von Human, Maus, Ratte, Hund, Meerschweinchen und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für CAPZA3 Antikörper (N-Term) (ABIN2787761)

Target: CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAPZA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CAPZA3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CAPZA3 Antibody - N-terminal region

Sequenz: MTLSVLSRKD KERVIRRLLL QAPPGEFVNA FDDLCLLIRD EKLMHHQGEC

Homologie: Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CAPZA3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAPZA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58604-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CAPZA3

Target: CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))

Andere Bezeichnung: CAPZA3

Hintergrund:

Targeted Subunit: alpha-3

Background Information: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA3 may play a role in the morphogenesis of spermatid.This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility.

Gene Name: Capping protein (actin filament) muscle Z-line, alpha 3

Alternative Symbols: Gsg3, CAPPA3, HEL-S-86

Protein Name: F-actin-capping protein subunit alpha-3

Molekulargewicht: 33kDa

Gen-ID: 93661

NCBI Accession: NP_201585

UniProt: Q96KX2

Pathways: Regulation of Actin Filament Polymerization