BPNT1 Antikörper (N-Term)
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- Target Alle BPNT1 Antikörper anzeigen
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Schwein, Hund, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BPNT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- DRVTIQELTA PLLTTAQAKP GETQEEETNS GEEPFIETPR QDGVSRRFIP
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 91%
- Produktmerkmale
- This is a rabbit polyclonal antibody against BPNT1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human BPNT1
- Top Product
- Discover our top product BPNT1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 261 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
- Andere Bezeichnung
- BPNT1 (BPNT1 Produkte)
- Synonyme
- BPNT1 antikoerper, PIP antikoerper, Sal3 antikoerper, BPntase antikoerper, 3'(2'), 5'-bisphosphate nucleotidase 1 antikoerper, bisphosphate 3'-nucleotidase 1 antikoerper, BPNT1 antikoerper, bpnt1.L antikoerper, Bpnt1 antikoerper
- Hintergrund
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BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Alias Symbols: PIP
Protein Interaction Partner: SUMO2, UBC, IQCB1,
Protein Size: 261 - Molekulargewicht
- 29 kDa
- Gen-ID
- 10380
- NCBI Accession
- NM_006085, NP_006076
- UniProt
- O95861
- Pathways
- Inositol Metabolic Process
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