BPNT1 Antikörper (N-Term)

Produktnummer ABIN2787757

Dieses Anti-BPNT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BPNT1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd und Schwein.

Kurzübersicht für BPNT1 Antikörper (N-Term) (ABIN2787757)

Target: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BPNT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BPNT1 Antikörper

Bindungsspezifität: N-Term

Sequenz: DRVTIQELTA PLLTTAQAKP GETQEEETNS GEEPFIETPR QDGVSRRFIP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against BPNT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BPNT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 261 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BPNT1

Target: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Andere Bezeichnung: BPNT1

Hintergrund: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Alias Symbols: PIP
Protein Interaction Partner: SUMO2, UBC, IQCB1,
Protein Size: 261

Molekulargewicht: 29 kDa

Gen-ID: 10380

NCBI Accession: NM_006085, NP_006076

UniProt: O95861

Pathways: Inositol Metabolic Process