Glucose-6-Phosphate Dehydrogenase Antikörper (Middle Region)
Kurzübersicht für Glucose-6-Phosphate Dehydrogenase Antikörper (Middle Region) (ABIN2787697)
Target
Alle Glucose-6-Phosphate Dehydrogenase (G6PD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- G6PD Antibody - middle region
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Sequenz
- VTKNIHESCM SQIGWNRIIV EKPFGRDLQS SDRLSNHISS LFREDQIYRI
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Homologie
- Cow: 85%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%, Sheep: 83%
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Produktmerkmale
- This is a rabbit polyclonal antibody against G6PD. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human G6PD
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58469-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Glucose-6-Phosphate Dehydrogenase (G6PD)
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Andere Bezeichnung
- G6PD
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Hintergrund
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Background Information: G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: Glucose-6-phosphate dehydrogenase
Alternative Symbols: G6PD1
Protein Name: Glucose-6-phosphate 1-dehydrogenase
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Molekulargewicht
- 57kDa
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Gen-ID
- 2539
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NCBI Accession
- NP_000393
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UniProt
- P11413
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
Target
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