Glucose-6-Phosphate Dehydrogenase Antikörper (Middle Region)

Produktnummer ABIN2787697

Dieses Anti-Glucose-6-Phosphate Dehydrogenase-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Glucose-6-Phosphate Dehydrogenase in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Schaf.

Kurzübersicht für Glucose-6-Phosphate Dehydrogenase Antikörper (Middle Region) (ABIN2787697)

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glucose-6-Phosphate Dehydrogenase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glucose-6-Phosphate Dehydrogenase Antikörper

Bindungsspezifität: Middle Region

Sequenz: VTKNIHESCM SQIGWNRIIV EKPFGRDLQS SDRLSNHISS LFREDQIYRI

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%, Sheep: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against G6PD. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human G6PD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 515 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Andere Bezeichnung: G6PD

Hintergrund: G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: G6PD1
Protein Interaction Partner: G6PD, SUMO2, UBC, MDM2, CKB, CAPN1, ALDH7A1, ZNF622, ZFYVE19, UBFD1, CNDP2, ISOC1, MAT2B, ERP44, YWHAQ, SLC9A3R1, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, EIF4H, VCL, UBE2V1, TGM2, PPP1R2, PGD, PAK2, LDHB, SFN, GNS, GLA, GBP2, EIF5, BAG3, FN1, CCT4, HARS, SUMO4
Protein Size: 515

Molekulargewicht: 57 kDa

Gen-ID: 2539

NCBI Accession: NM_000402, NP_000393

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones