FRS3 Antikörper (C-Term)

Produktnummer ABIN2787696

Produktdetails anti-FRS3 Antikörper

Target: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FRS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: APGPTPHPVR SSDSYAVIDL KKTAAMSDLQ RALPRDDGAV RKTRHNSTDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Frs3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Frs3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 492 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FRS3

Target: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Andere Bezeichnung: Frs3 (FRS3 Produkte)

Hintergrund: Frs3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. It is involved in the activation of MAP kinases. Frs3 Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Alias Symbols: 4930417B13Rik, AI449674, Frs2beta, MGC25496, Snt2
Protein Interaction Partner: Bmpr2,
Protein Size: 492

Molekulargewicht: 54 kDa

Gen-ID: 107971

NCBI Accession: NM_144939, NP_659188

UniProt: Q91WJ0