APRT Antikörper (N-Term)

Produktnummer ABIN2787672

Dieses Anti-APRT-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von APRT in WB und IHC. Geeignet für Human, Ratte, Hund, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für APRT Antikörper (N-Term) (ABIN2787672)

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APRT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-APRT Antikörper

Bindungsspezifität: N-Term

Sequenz: ADSELQLVEQ RIRSFPDFPT PGVVFRDISP VLKDPASFRA AIGLLARHLK

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against APRT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human APRT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 180 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu APRT

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Andere Bezeichnung: APRT

Hintergrund: Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961
Protein Interaction Partner: UBC, FN1, VCAM1, MLH1, ITGA4, NAPRT, HECW2, GMPS, UMPS, HPRT1, APP, IKBKG, APRT, VHL,
Protein Size: 180

Molekulargewicht: 20 kDa

Gen-ID: 353

NCBI Accession: NM_000485, NP_000476

UniProt: P07741

Pathways: Ribonucleoside Biosynthetic Process