MECOM Antikörper (N-Term)
Kurzübersicht für MECOM Antikörper (N-Term) (ABIN2787657)
Target
Alle MECOM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- VKGLSSTEQT NKSQSPLMTH PQILPATQDI LKALSKHPSV GDNKPVELQP
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against EVI1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human EVI1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 1051 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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Andere Bezeichnung
- EVI1
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Hintergrund
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EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity.
Alias Symbols: AML1-EVI-1, EVI-1, MDS1-EVI1, MGC163392, PRDM3, EVI1, MDS1
Protein Interaction Partner: PRMT1, PIAS4, SUMO1, SOX2, ELAVL1, SIRT1, KAT2B, SMAD4, SMAD3, SMAD2, SMAD1, EHMT2, SUV39H1, MECOM, HDAC1, HDAC4, CTBP2, CTBP1, CREBBP, MBD3,
Protein Size: 1051 -
Molekulargewicht
- 118 kDa
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Gen-ID
- 2122
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NCBI Accession
- NM_005241, NP_005232
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UniProt
- Q03112
Target
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