TNKS1BP1 Antikörper (Middle Region)

Produktnummer ABIN2787645

Der Kaninchen Polyklonal anti-TNKS1BP1 Antikörper (ABIN2787645) detektiert spezifisch TNKS1BP1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TNKS1BP1 Antikörper (Middle Region) (ABIN2787645)

Target: TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNKS1BP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TNKS1BP1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DGEASQTEDV DGTWGSSAAR WSDQGPAQTS RRPSQGPPAR SPSQDFSFIE

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNKS1BP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TNKS1BP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1729 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNKS1BP1

Target: TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))

Andere Bezeichnung: TNKS1BP1

Hintergrund: TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
Alias Symbols: FLJ45975, KIAA1741, TAB182
Protein Interaction Partner: UBC, RNF219, SPC25, RABGEF1, DCTN3, SPTBN1, NLK, CSNK2A1, CNOT6L, CNOT6, VCP, HNRNPK, DYNC1H1, CBX3, SIRT7, TSG101, Cnot3, Capza1, TNKS2, TNKS,
Protein Size: 1729

Molekulargewicht: 190 kDa

Gen-ID: 85456

NCBI Accession: NM_033396, NP_203754

UniProt: Q9C0C2