CENPH Antikörper (Middle Region)

Produktnummer ABIN2787617

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-CENPH Antikörper wird verwendet zum Nachweis von CENPH in Proben von Human, Maus, Ratte, Schwein, Hund, Pferd, Rind (Kuh), Meerschweinchen und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für CENPH Antikörper (Middle Region) (ABIN2787617)

Target: CENPH (Centromere Protein H (CENPH))

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CENPH Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: CENPH Antibody - middle region

Sequenz: ESWDLEEKLL DIRKKRLQLK QASESKLLEI QTEKNKQKID LDSMENSERI

Homologie: Cow: 93%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CENPH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CENPH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58266-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CENPH Antikörper (ABIN2787617)

Liao, Zhang, Zhou, Zimonjic, Mani, Kaba, Gifford, Reinhardt, Popescu, Guo, Eaton, Lodish, Weinberg: "Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity." in: Cancer research, Vol. 67, Issue 17, pp. 8131-8, (2007) (PubMed).

Details zu CENPH

Target: CENPH (Centromere Protein H (CENPH))

Andere Bezeichnung: CENPH

Hintergrund:

Background Information: Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Centromere protein H

Alternative Symbols: NNF1, PMF1

Protein Name: Centromere protein H

Molekulargewicht: 27kDa

Gen-ID: 64946

NCBI Accession: NP_075060

UniProt: Q9H3R5