DUSP5 Antikörper (Middle Region)

Produktnummer ABIN2787599

Dieses Anti-DUSP5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DUSP5 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen und Schwein.

Kurzübersicht für DUSP5 Antikörper (Middle Region) (ABIN2787599)

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DUSP5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AGSSLIGHLQ TLSPDMQGAY CTFPASVLAP VPTHSTVSEL SRSPVATATS

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against DUSP5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DUSP5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 384 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DUSP5

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Andere Bezeichnung: DUSP5

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Alias Symbols: DUSP, HVH3
Protein Interaction Partner: ELAVL1, UBC, MAPK3, MAPK1,
Protein Size: 384

Molekulargewicht: 42 kDa

Gen-ID: 1847

NCBI Accession: NM_004419, NP_004410

UniProt: Q16690