A2BP1 Antikörper (Middle Region)

Produktnummer ABIN2787590

Der Kaninchen Polyklonal anti-A2BP1 Antikörper wird verwendet zum Nachweis von A2BP1 in Proben von Human, Maus, Rind (Kuh), Hund, Pferd und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für A2BP1 Antikörper (Middle Region) (ABIN2787590)

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser A2BP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-A2BP1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: A2BP1 Antibody - middle region

Sequenz: TAAAYSDRNQ FVFVAADEIS CNTSAVTDEF MLPTPTTTHL LQPPPTALVP

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against A2BP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human A2BP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58203-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Andere Bezeichnung: A2BP1

Hintergrund:

Background Information: Ataxin-2 binding protein 1(A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Four alternatively spliced transcript variants have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.

Gene Name: RNA binding protein, fox-1 homolog (C. elegans) 1

Alternative Symbols: 2BP1, FOX1, A2BP1, FOX-1, HRNBP1

Protein Name: RNA binding protein fox-1 homolog 1

Molekulargewicht: 42kDa

Gen-ID: 54715

NCBI Accession: NP_665900

UniProt: Q9NWB1