TRIM25 Antikörper (Middle Region)

Produktnummer ABIN2787551

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TRIM25 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh) und Schwein.

Kurzübersicht für TRIM25 Antikörper (Middle Region) (ABIN2787551)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reaktivität: Human, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRIM25 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TRIM25 Antibody - middle region

Sequenz: TPSSGDPGEH DPASTHKSTR PVKKVSKEEK KSKKPPPVPA LPSKLPTFGA

Homologie: Cow: 91%, Human: 100%, Pig: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIM25. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM25

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58106-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25

Hintergrund:

Background Information: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Gene Name: Tripartite motif containing 25

Alternative Symbols: EFP, Z147, RNF147, ZNF147

Protein Name: E3 ubiquitin/ISG15 ligase TRIM25

Molekulargewicht: 71kDa

Gen-ID: 7706

NCBI Accession: NP_005073

UniProt: Q14258