TRIM25 Antikörper (Middle Region)

Produktnummer ABIN2787550

Dieses Anti-TRIM25-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRIM25 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen und Pferd.

Kurzübersicht für TRIM25 Antikörper (Middle Region) (ABIN2787550)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRIM25 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LLDASETTST RKIKEEEKRV NSKFDTIYQI LLKKKSEIQT LKEEIEQSLT

Homologie: Cow: 79%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIM25. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM25

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 630 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25

Hintergrund: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Alias Symbols: EFP, RNF147, Z147, ZNF147
Protein Interaction Partner: UBC, DDX58, SUMO2, AMFR, UBE2D1, SUMO1, PCNA, USP15, UBA1, RPS27A, RPA1, KIF5B, HSPA1L, HSPA1B, HSPA1A, EEF1A2, ACLY, SUZ12, RNF2, EZH2, BMI1, HECW2, TRIM25, TRIM8, TFG, GRIK2, ESR1, OTUB2, USP39, VCP, WARS, UAP1, UBXN6, UBE2S, UBE2D2, TRAF6, ISG15, UBE2D
Protein Size: 630

Molekulargewicht: 71 kDa

Gen-ID: 7706

NCBI Accession: NM_005082, NP_005073

UniProt: Q14258