CEBPA Antikörper (C-Term)

Produktnummer ABIN2787466

Dieses Anti-CEBPA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CEBPA in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Hund und Kaninchen.

Kurzübersicht für CEBPA Antikörper (C-Term) (ABIN2787466)

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CEBPA Antikörper

Bindungsspezifität: C-Term

Sequenz: ASGGSGAGKA KKSVDKNSNE YRVRRERNNI AVRKSRDKAK QRNVETQQKV

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CEBPA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CEBPA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 358 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Andere Bezeichnung: CEBPA

Hintergrund: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Alias Symbols: C/EBP-alpha, CEBP
Protein Interaction Partner: CEBPB, ZBTB16, RARA, HDAC1, BHLHE41, UBC, CEBPE, BATF2, BATF3, YY1AP1, ATF5, BATF, FOSL1, FOS, DBP, CEBPG, CEBPA, ATF4, ATF3, UBE3A, SKP2, RASGRF1, C1QBP, CDKN1A, SRA1, CDK4, PIAS1, Fbxw7, GRIN3A, RAB34, NAA16, POLR1E, MRTO4, AK5, MACF1, KAT5, AKAP9, SMC1
Protein Size: 358

Molekulargewicht: 37 kDa

Gen-ID: 1050

NCBI Accession: NM_004364, NP_004355

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation