MED16 Antikörper (Middle Region)

Produktnummer ABIN2787461

Der Kaninchen Polyklonal anti-MED16 Antikörper (ABIN2787461) detektiert spezifisch MED16 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für MED16 Antikörper (Middle Region) (ABIN2787461)

Target: MED16 (Mediator Complex Subunit 16 (MED16))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MED16 Antikörper

Bindungsspezifität: Middle Region

Sequenz: IVALSWLHNG VKLALHVEKS GASSFGEKFS RVKFSPSLTL FGGKPMEGWI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MED16. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MED16

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MED16

Target: MED16 (Mediator Complex Subunit 16 (MED16))

Andere Bezeichnung: MED16

Hintergrund: MED16 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. It mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Interaction Partner: HECW2, CDK19, CDK8, UBC, MED19, MED26, EPAS1, FBXW7, MED11, MED8, MED29, MED9, MED18, MED4, RALY, MED13, MED12, MED24, MED21, MED14, MED1, CTDP1, HIST1H3A, MED10, MED25, MED15, VDR, TRA, MED28, OBFC1, ZC3H13, QKI, TADA2A, SUPT7L, SUPT3H, MYC, KAT2A, TRRAP
Protein Size: 663

Molekulargewicht: 72 kDa

Gen-ID: 10025

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha