ORC4 Antikörper (Middle Region)

Produktnummer ABIN2787391

Produktdetails anti-ORC4 Antikörper

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VLEICLIIAM KHLNDIYEEE PFNFQMVYNE FQKFVQRKAH SVYNFEKPVV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ORC4L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ORC4L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 436 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ORC4

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Andere Bezeichnung: ORC4L (ORC4 Produkte)

Hintergrund: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves
Alias Symbols: ORC4, ORC4P, ORC4L
Protein Interaction Partner: RRM2B, TCF4, MCM3, MTUS1, MCM10, FBXL8, FBXO6, FBXO25, FBXL5, ORC3, ORC6, UBC, ORC5, ORC2, MLH1, MCM7, KPNA1, CTBP1, CDKN2A, CCND1, APP, XRCC5, XRCC6, CCL2, tat, MCM2, ORC1, MCM6, MCM4, DBF4, RPA2,
Protein Size: 436

Molekulargewicht: 50 kDa

Gen-ID: 5000

NCBI Accession: NM_181741, NP_859525

UniProt: O43929

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA