SMEK1 Antikörper (Middle Region)

Produktnummer ABIN2787340

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMEK1 in WB. Er zeigt eine Reaktivität gegenüber Maus, Human, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für SMEK1 Antikörper (Middle Region) (ABIN2787340)

Target: SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))

Reaktivität: Maus, Human, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMEK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMEK1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: YWKALEDVDY VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SMEK1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMEK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 820 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMEK1

Target: SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))

Andere Bezeichnung: SMEK1

Hintergrund: SMEK1 is the regulatory subunit of serine/threonine-protein phosphatase 4.SMEK1 may regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: FLFL1, KIAA2010, MSTP033, smk-1, smk1, PP4R3A
Protein Interaction Partner: HUWE1, UBC, PPP4R2, BRCC3, SF3A1, HNRNPR, TELO2, MTA2, PSMB1, PSMA2, DDB2, CAST, ARCN1, AMPD2, ACACA, CASK, POLR2A, IGBP1, PPP4C, HDAC1, MAPK14,
Protein Size: 820

Molekulargewicht: 94 kDa

Gen-ID: 55671

NCBI Accession: NM_032560, NP_115949

Pathways: Regulation of Carbohydrate Metabolic Process