TRIB3 Antikörper (N-Term)

Produktnummer ABIN2787259

Der Kaninchen Polyklonal anti-TRIB3 Antikörper wird verwendet zum Nachweis von TRIB3 in Proben von Human, Ratte, Rind (Kuh), Schaf, Meerschweinchen, Kaninchen und Hund. Er wurde validiert für WB.

Kurzübersicht für TRIB3 Antikörper (N-Term) (ABIN2787259)

Target: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Reaktivität: Human, Ratte, Rind (Kuh), Schaf, Meerschweinchen, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRIB3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TRIB3 Antibody - N-terminal region

Sequenz: YVLLEPEEGG RAYQALHCPT GTEYTCKVYP VQEALAVLEP YARLPPHKHV

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Rabbit: 86%, Rat: 79%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIB3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIB3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57518-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIB3

Target: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Andere Bezeichnung: TRIB3

Hintergrund:

Background Information: The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.

Gene Name: Tribbles homolog 3 (Drosophila)

Alternative Symbols: NIPK, SINK, TRB3, SKIP3, C20orf97

Protein Name: Tribbles homolog 3

Molekulargewicht: 39kDa

Gen-ID: 57761

NCBI Accession: NP_066981

UniProt: Q96RU7

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha