TRIB3 Antikörper (N-Term)

Produktnummer ABIN2787258

Produktdetails anti-TRIB3 Antikörper

Target: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Schaf, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KNNRMSANND HFLTPTWQQM RATPLAAPAG SLSRKKRLEL DDNLDTERPV

Homologie: Cow: 91%, Human: 100%, Pig: 91%, Sheep: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIB3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human TRIB3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIB3

Target: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Andere Bezeichnung: TRIB3 (TRIB3 Produkte)

Synonyme: zgc:76966 antikoerper, TRIB3 antikoerper, C20orf97 antikoerper, NIPK antikoerper, SINK antikoerper, SKIP3 antikoerper, TRB3 antikoerper, Ifld2 antikoerper, Nipk antikoerper, TRB-3 antikoerper, Trb3 antikoerper, tribbles pseudokinase 3 antikoerper, trib3 antikoerper, TRIB3 antikoerper, Trib3 antikoerper

Hintergrund: The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.
Alias Symbols: NIPK, SINK, TRB3, SKIP3, C20orf97
Protein Size: 385

Molekulargewicht: 42 kDa

Gen-ID: 57761

NCBI Accession: NM_001301201, NP_001288130

UniProt: J3KR25

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha