CHMP1B Antikörper (N-Term)

Produktnummer ABIN2787213

Der Kaninchen Polyklonal anti-CHMP1B Antikörper wird verwendet zum Nachweis von CHMP1B in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Zebrafisch (Danio rerio) und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für CHMP1B Antikörper (N-Term) (ABIN2787213)

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHMP1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CHMP1B Antikörper

Bindungsspezifität: N-Term

Sequenz: KIKKAIQKGN MEVARIHAEN AIRQKNQAVN FLRMSARVDA VAARVQTAVT

Homologie: Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CHMP1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHMP1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 199 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CHMP1B

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Andere Bezeichnung: CHMP1B

Hintergrund: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Alias Symbols: C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2
Protein Interaction Partner: STAMBP, UBC, ATP6V1B1, CHMP4B, KNSTRN, CHMP1B, CHMP5, VPS4A, CNOT10, SNRNP200, SUCLG1, RAB11A, RASSF7, SSRP1, CHMP1A, USP54, USP8, SPAST, ELAVL1, IST1, VPS4B,
Protein Size: 199

Molekulargewicht: 22 kDa

Gen-ID: 57132

NCBI Accession: NM_020412, NP_065145

UniProt: Q7LBR1