EIF5A2 Antikörper (N-Term)
Kurzübersicht für EIF5A2 Antikörper (N-Term) (ABIN2787209)
Target
Alle EIF5A2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MADEIDFTTG DAGASSTYPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against EIF5A2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human EIF5A2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 153 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF5A2 (Eukaryotic Translation Initiation Factor 5A2 (EIF5A2))
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Andere Bezeichnung
- EIF5A2
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Hintergrund
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EIF5A2 is a mRNA-binding protein involved in translation elongation. EIF5A2 has an important function at the level of mRNA turnover, probably acting downstream of decapping.EIF5A2 is involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. EIF5A2 functions as a regulator of apoptosis.EIF5A2 mediates effects of polyamines on neuronal process extension and survival.EIF5A2 may play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
Alias Symbols: EIF-5A2, eIF5AII
Protein Interaction Partner: NIF3L1, CDC23, SDCBP, REL, DHPS, FAM96B, UBC, MDM2, PTBP2, RAB30, CUL3, CUL4B, CDK2, VHL, OPTN, DCC,
Protein Size: 153 -
Molekulargewicht
- 17 kDa
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Gen-ID
- 56648
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NCBI Accession
- NM_020390, NP_065123
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UniProt
- Q9GZV4
Target
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