ELP2 Antikörper (Middle Region)

Produktnummer ABIN2787102

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ELP2 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für ELP2 Antikörper (Middle Region) (ABIN2787102)

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ELP2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: EESGVWLEQV RVGEVGGNTL GFYDCQFNED GSMIIAHAFH GALHLWKQNT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ELP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ELP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 826 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ELP2

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Andere Bezeichnung: ELP2

Hintergrund: ELP2 regulates the ligand-dependent activation of STAT3. ELP2 acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
Alias Symbols: FLJ10879, SHINC-2, STATIP1, StIP
Protein Interaction Partner: UBC, FAM96B, CIAO1, PAAF1, WRNIP1, ELP3, NRBP1, CD2AP, KIAA1033, USP34, SNRPB2, PRPSAP2, KIF5B, MMS19, IKBKAP, ELP4, CTDP1, STAT5B, STAT1, JAK2, JAK1, STAT3, TYK2,
Protein Size: 826

Molekulargewicht: 92 kDa

Gen-ID: 55250

NCBI Accession: NM_018255, NP_060725

UniProt: Q6IA86

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus