Acylglycerol Kinase Antikörper (N-Term)

Produktnummer ABIN2787097

Produktdetails anti-Acylglycerol Kinase Antikörper

Target: Acylglycerol Kinase (AGK)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acylglycerol Kinase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DNLLRRAACQ EAQVFGNQLI PPNAQVKKAT VFLNPAACKG KARTLFEKNA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AGK. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AGK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 422 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Acylglycerol Kinase

Target: Acylglycerol Kinase (AGK)

Andere Bezeichnung: AGK (AGK Produkte)

Synonyme: mulk antikoerper, CATC5 antikoerper, CTRCT38 antikoerper, MTDPS10 antikoerper, MULK antikoerper, 2610037M15Rik antikoerper, 6720408I04Rik antikoerper, AI465370 antikoerper, Mulk antikoerper, RGD1562046 antikoerper, fi38e09 antikoerper, wu:fi38e09 antikoerper, zgc:55462 antikoerper, acylglycerol kinase antikoerper, acylglycerol kinase S homeolog antikoerper, AGK antikoerper, agk antikoerper, LOC100165096 antikoerper, Agk antikoerper, agk.S antikoerper

Hintergrund: AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: PCSK9, UBC, RNF2, BMI1, PARK2, FBXO6, UBD, CUL3, AGO4, RYK, ICT1, SNX4, PDLIM1, HCK,
Protein Size: 422

Molekulargewicht: 47 kDa

Gen-ID: 55750

NCBI Accession: NM_018238, NP_060708

UniProt: Q53H12