Tescalcin Antikörper (C-Term)

Produktnummer ABIN2787042

Produktdetails anti-Tescalcin Antikörper

Target: Tescalcin (TESC)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tescalcin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DSDGRITLEE YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against TESC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TESC

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Tescalcin

Target: Tescalcin (TESC)

Andere Bezeichnung: TESC (TESC Produkte)

Hintergrund: TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane and promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner and inhibits the phosphatase activity of calcineurin.
Alias Symbols: CHP3, TSC
Protein Interaction Partner: WBP11, UBC, CCDC91, HMG20A, TESC, RAI1, DYNLT3, SLC9A1,
Protein Size: 214

Molekulargewicht: 23 kDa

Gen-ID: 54997

NCBI Accession: NM_017899, NP_060369

UniProt: Q96BS2

Pathways: Proton Transport