PNRC2 Antikörper (Middle Region)

Produktnummer ABIN2787028

Produktdetails anti-PNRC2 Antikörper

Target: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNRC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NQSWNSSLSG PRLLFKSQAN QNYAGAKFSE PPSPSVLPKP PSHWVPVSFN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PNRC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PNRC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 139 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PNRC2

Target: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Andere Bezeichnung: PNRC2 (PNRC2 Produkte)

Synonyme: 0610011E17Rik antikoerper, D4Bwg0593e antikoerper, wu:cegs2777 antikoerper, wu:fb51a04 antikoerper, wu:fb81a06 antikoerper, wu:fd19g06 antikoerper, proline rich nuclear receptor coactivator 2 antikoerper, proline-rich nuclear receptor coactivator 2 antikoerper, PNRC2 antikoerper, Pnrc2 antikoerper, pnrc2 antikoerper

Hintergrund: PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure.
Alias Symbols: FLJ20312, MGC99541
Protein Interaction Partner: DCP1A, ESRRG, UBC, SF1, GLOD4, SPAG9, ZBTB48, XRCC6, RORA, RARG, HNF4G, HNF4A, NR5A2, ESR2, ESR1, ZBTB16, RORB, ESRRA, RARA, AR, NR5A1,
Protein Size: 139

Molekulargewicht: 15 kDa

Gen-ID: 55629

NCBI Accession: NM_017761, NP_060231

UniProt: Q9NPJ4