PNRC2 Antikörper (Middle Region)

Produktnummer ABIN2787028

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PNRC2 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Hund und Zebrafisch (Danio rerio).

Kurzübersicht für PNRC2 Antikörper (Middle Region) (ABIN2787028)

Target: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Reaktivität: Human, Ratte, Maus, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNRC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PNRC2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: NQSWNSSLSG PRLLFKSQAN QNYAGAKFSE PPSPSVLPKP PSHWVPVSFN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PNRC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PNRC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 139 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PNRC2

Target: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Andere Bezeichnung: PNRC2

Hintergrund: PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure.
Alias Symbols: FLJ20312, MGC99541
Protein Interaction Partner: DCP1A, ESRRG, UBC, SF1, GLOD4, SPAG9, ZBTB48, XRCC6, RORA, RARG, HNF4G, HNF4A, NR5A2, ESR2, ESR1, ZBTB16, RORB, ESRRA, RARA, AR, NR5A1,
Protein Size: 139

Molekulargewicht: 15 kDa

Gen-ID: 55629

NCBI Accession: NM_017761, NP_060231

UniProt: Q9NPJ4