PNPLA8 Antikörper (Middle Region)

Produktnummer ABIN504075

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-PNPLA8 Antikörper (ABIN504075) detektiert spezifisch PNPLA8 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für PNPLA8 Antikörper (Middle Region) (ABIN504075)

Target: PNPLA8 (Patatin-Like phospholipase Domain Containing 8 (PNPLA8))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNPLA8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PNPLA8 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: PNPLA8 Antibody - middle region

Sequenz: IDNRTRALVQ ALRRTTDPKL CITRVEELTF HLLEFPEGKG VAVKERIIPY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PNPLA8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PNPLA8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56759-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PNPLA8 Antikörper (ABIN504075)

Ali, Kokotos, Magrioti, Bone, Mobley, Hancock, Ramanadham: "Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetes." in: PLoS ONE, Vol. 8, Issue 8, pp. e71748, (2013) (PubMed).

Details zu PNPLA8

Target: PNPLA8 (Patatin-Like phospholipase Domain Containing 8 (PNPLA8))

Andere Bezeichnung: PNPLA8

Hintergrund:

Background Information: Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflam

Gene Name: Patatin-like phospholipase domain containing 8

Alternative Symbols: MMLA, IPLA2G, IPLA2-2, iPLA2gamma, PNPLA-gamma

Protein Name: Calcium-independent phospholipase A2-gamma

Molekulargewicht: 88 kDa

Gen-ID: 50640

NCBI Accession: NP_056538

UniProt: Q9NP80