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PSMA2 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-PSMA2-Antikörper wurde für WB validiert. Er ist geeignet, PSMA2 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Schaf und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2786711

Kurzübersicht für PSMA2 Antikörper (N-Term) (ABIN2786711)

Target

Alle PSMA2 Antikörper anzeigen
PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Reaktivität

  • 49
  • 30
  • 27
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Schaf, Zebrafisch (Danio rerio)

Wirt

  • 47
  • 2
  • 1
Kaninchen

Klonalität

  • 45
  • 5
Polyklonal

Konjugat

  • 26
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PSMA2 Antikörper ist unkonjugiert

Applikation

  • 38
  • 13
  • 11
  • 10
  • 7
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    VGIKAANGVV LATEKKQKSI LYDERSVHKV EPITKHIGLV YSGMGPDYRV

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against PSMA2. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human PSMA2
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 234 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target

    PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

    Andere Bezeichnung

    PSMA2

    Hintergrund

    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA2 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HC3, MU, PMSA2, PSC2
    Protein Interaction Partner: HUWE1, UBC, PSMD14, MDM2, ASB11, POMP, PSMG3, PSMG1, PSME4, KIF5B, SMEK1, PSMB8, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PSMA3, PSMA1, PARK2, BAG3, FBXW4, IQCB1, HOMER3, FN1, NOS2, PSMB10, PSMB9, PSMA2, PR39, PSMD13, P
    Protein Size: 234

    Molekulargewicht

    26 kDa

    Gen-ID

    5683

    NCBI Accession

    NM_002787, NP_002778

    UniProt

    P25787

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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