PIM1 Antikörper (N-Term)
Kurzübersicht für PIM1 Antikörper (N-Term) (ABIN2786676)
Target
Alle PIM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- PIM1 Antibody - N-terminal region
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Sequenz
- MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PIM1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56390-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PIM1 (Pim-1 Oncogene (PIM1))
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Andere Bezeichnung
- PIM1
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Hintergrund
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Background Information: PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and
Gene Name: Pim-1 oncogene
Alternative Symbols: PIM
Protein Name: Serine/threonine-protein kinase pim-1
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Molekulargewicht
- 45kDa
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Gen-ID
- 5292
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NCBI Accession
- NP_002639
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UniProt
- P11309
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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