PIM1 Antikörper (N-Term)

Produktnummer ABIN2786676

Der Kaninchen Polyklonal Anti-PIM1-Antikörper wurde für WB validiert. Er ist geeignet, PIM1 in Proben von Human, Maus, Ratte, Pferd, Schaf, Rind (Kuh), Hund, Kaninchen und Meerschweinchen zu detektieren.

Kurzübersicht für PIM1 Antikörper (N-Term) (ABIN2786676)

Target: PIM1 (Pim-1 Oncogene (PIM1))

Reaktivität: Human, Maus, Ratte, Pferd, Schaf, Rind (Kuh), Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIM1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PIM1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 313 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PIM1

Target: PIM1 (Pim-1 Oncogene (PIM1))

Andere Bezeichnung: PIM1

Hintergrund: PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and
Alias Symbols: PIM
Protein Interaction Partner: FXR2, NHLH1, FH, BEND7, HEXIM2, BANP, TFPT, ZBTB1, UBC, APP, MARK3, HSP90AA1, HSPA4, PIM1, MDM2, ELAVL1, FZR1, SKP2, PPP2R5E, PPP2R4, PPP2CA, PIN1, CDC34, CDC20, ABCB1, HIST2H3C, MYC, MAX, SNX6, CBX1, CBX3, BAD, HIST3H3, SND1, PTPRO, NFATC1, SHMT1, EPHA3,
Protein Size: 404

Molekulargewicht: 45 kDa

Gen-ID: 5292

NCBI Accession: NM_002648, NP_002639

Pathways: Glycosaminoglycan Metabolic Process