PIM1 Antikörper (N-Term)
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- Target Alle PIM1 Antikörper anzeigen
- PIM1 (Pim-1 Oncogene (PIM1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Pferd, Kaninchen, Schaf, Rind (Kuh), Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PIM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PIM1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1
- Top Product
- Discover our top product PIM1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 313 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PIM1 (Pim-1 Oncogene (PIM1))
- Andere Bezeichnung
- PIM1 (PIM1 Produkte)
- Synonyme
- PIM antikoerper, Pim-1 antikoerper, PIM1 antikoerper, pim antikoerper, pim-1 antikoerper, pim3 antikoerper, Pim-1 proto-oncogene, serine/threonine kinase antikoerper, proviral integration site 1 antikoerper, Pim-1 proto-oncogene, serine/threonine kinase L homeolog antikoerper, PIM1 antikoerper, Pim1 antikoerper, pim1 antikoerper, pim1.L antikoerper
- Hintergrund
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The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.
Alias Symbols: PIM
Protein Interaction Partner: FXR2, NHLH1, FH, BEND7, HEXIM2, BANP, TFPT, ZBTB1, UBC, APP, MARK3, HSP90AA1, HSPA4, PIM1, MDM2, ELAVL1, FZR1, SKP2, PPP2R5E, PPP2R4, PPP2CA, PIN1, CDC34, CDC20, ABCB1, HIST2H3C, MYC, MAX, SNX6, CBX1, CBX3, BAD, HIST3H3, SND1, PTPRO, NFATC1, SHMT1, EPHA3,
Protein Size: 313 - Molekulargewicht
- 36 kDa
- Gen-ID
- 5292
- NCBI Accession
- NM_002648, NP_002639
- Pathways
- Glycosaminoglycan Metabolic Process
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