MTMR12 Antikörper (Middle Region)
Kurzübersicht für MTMR12 Antikörper (Middle Region) (ABIN2786614)
Target
Alle MTMR12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - Middle Region
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Sequenz
 - RNSARLSSLF PFALLQRHSS KPVLPTSGWK ALGDEDDLAK REDEFVDLGD
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Homologie
 - Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
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Produktmerkmale
 - This is a rabbit polyclonal antibody against MTMR12. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
 - Affinity Purified
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Immunogen
 - The immunogen is a synthetic peptide directed towards the middle region of human MTMR12
 
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Applikationshinweise
 - Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 747 AA
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - Lot specific
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Buffer
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
 - Avoid repeated freeze-thaw cycles.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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- MTMR12 (Myotubularin Related Protein 12 (MTMR12))
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Andere Bezeichnung
 - MTMR12
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Hintergrund
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                        MTMR12 inactives phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Alias Symbols: 3-PAP, PIP3AP
Protein Interaction Partner: YWHAB, UBC, MTM1,
Protein Size: 747 - 
                                            
Molekulargewicht
 - 86 kDa
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Gen-ID
 - 54545
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NCBI Accession
 - NM_001040446, NP_001035536
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UniProt
 - Q9C0I1
 
Target
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