P5CS Antikörper (N-Term)
-
- Target Alle P5CS (ALDH18A1) Antikörper anzeigen
- P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
-
Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser P5CS Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- SVIRHVRSWS NIPFITVPLS RTHGKSFAHR SELKHAKRIV VKLGSAVVTR
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ALDH18A1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALDH18A1
- Top Product
- Discover our top product ALDH18A1 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 793 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
- Andere Bezeichnung
- ALDH18A1 (ALDH18A1 Produkte)
- Synonyme
- ALDH18A1 antikoerper, ARCL3A antikoerper, GSAS antikoerper, P5CS antikoerper, PYCS antikoerper, 2810433K04Rik antikoerper, AI429789 antikoerper, Pycs antikoerper, cb842 antikoerper, cb899 antikoerper, pycs antikoerper, sb:cb881 antikoerper, wu:fa91f10 antikoerper, wu:fi05f11 antikoerper, wu:fi17d12 antikoerper, aldehyde dehydrogenase 18 family member A1 antikoerper, aldehyde dehydrogenase 18 family, member A1 antikoerper, aldehyde dehydrogenase 18 family member A1 L homeolog antikoerper, ALDH18A1 antikoerper, aldh18a1 antikoerper, Aldh18a1 antikoerper, aldh18a1.L antikoerper
- Hintergrund
-
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases.This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
Alias Symbols: GSAS, MGC117316, P5CS, PYCS, ARCL3A
Protein Interaction Partner: CMTM5, AGTRAP, UBC, SUMO2, SUMO3, STAU1, MDM2, LATS2, ADRB2, VCP, TIMM13, SUMO1, NONO, MTHFD1, ILF3, ILF2, DDX1, CUL3, CDK2, SIRT7, TCF3, Haus1, Mical3, Trim69, Cbx1, HDAC5, MYC, ICT1, ZRANB1,
Protein Size: 793 - Molekulargewicht
- 87 kDa
- Gen-ID
- 5832
- NCBI Accession
- NM_001017423, NP_001017423
- UniProt
- P54886
-