GOPC Antikörper (N-Term)

Produktnummer ABIN2786578

Der Kaninchen Polyklonal anti-GOPC Antikörper (ABIN2786578) detektiert spezifisch GOPC in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für GOPC Antikörper (N-Term) (ABIN2786578)

Target: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GOPC Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GOPC Antibody - N-terminal region

Sequenz: EVLEKEFDKA FVDVDLLLGE IDPDQADITY EGRQKMTSLS SCFAQLCHKA

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GOPC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GOPC

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56214-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GOPC

Target: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Andere Bezeichnung: GOPC

Hintergrund:

Background Information: GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].

Gene Name: Golgi-associated PDZ and coiled-coil motif containing

Alternative Symbols: CAL, FIG, PIST, GOPC1, dJ94G16.2

Protein Name: Golgi-associated PDZ and coiled-coil motif-containing protein

Molekulargewicht: 50kDa

Gen-ID: 57120

NCBI Accession: NP_001017408

UniProt: Q9HD26

Pathways: Maintenance of Protein Location, Asymmetric Protein Localization