PPOX Antikörper (N-Term)

Produktnummer ABIN2786509

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-PPOX Antikörper wird verwendet zum Nachweis von PPOX in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund und Schwein. Er wurde validiert für WB.

Kurzübersicht für PPOX Antikörper (N-Term) (ABIN2786509)

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PPOX Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PPOX Antibody - N-terminal region

Sequenz: SSERLGGWIR SVRGPNGAIF ELGPRGIRPA GALGARTLLL VSELGLDSEV

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PPOX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPOX

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56095-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PPOX Antikörper (ABIN2786509)

de Vooght, van Wijk, van Solinge: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." in: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).

Details zu PPOX

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Andere Bezeichnung: PPOX

Hintergrund:

Background Information: PPOX catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX..This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene Name: Protoporphyrinogen oxidase

Alternative Symbols: VP, PPO, V290M

Protein Name: Protoporphyrinogen oxidase

Molekulargewicht: 51kDa

Gen-ID: 5498

NCBI Accession: NP_000300

UniProt: P50336

Pathways: Synaptic Membrane, Feeding Behaviour