Monoamine Oxidase A Antikörper (N-Term)

Produktnummer ABIN2786499

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Monoamine Oxidase A Antikörper wird verwendet zum Nachweis von Monoamine Oxidase A in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen und Pferd. Er wurde validiert für WB.

Kurzübersicht für Monoamine Oxidase A Antikörper (N-Term) (ABIN2786499)

Target: Monoamine Oxidase A (MAOA)

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Monoamine Oxidase A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Monoamine Oxidase A Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MAOA Antibody - N-terminal region

Sequenz: GPTQNRILRL SKELGIETYK VNVSERLVQY VKGKTYPFRG AFPPVWNPIA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against MAOA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAOA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56074-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Monoamine Oxidase A Antikörper (ABIN2786499)

Neumann, Grobe, Weisgut, Schwelberger, Fogel, Marušáková, Wache, Bähre, Buchwalow, Dhein, Hofmann, Kirchhefer, Gergs: "Histamine can be Formed and Degraded in the Human and Mouse Heart." in: Frontiers in pharmacology, Vol. 12, pp. 582916, (2021) (PubMed).

Details zu Monoamine Oxidase A

Target: Monoamine Oxidase A (MAOA)

Andere Bezeichnung: MAOA

Hintergrund:

Background Information: MAOA catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Monoamine oxidase A

Alternative Symbols: BRNRS, MAO-A

Protein Name: Amine oxidase [flavin-containing] A

Molekulargewicht: 60kDa

Gen-ID: 4128

NCBI Accession: NP_000231

UniProt: P21397