HIPK1 Antikörper (Middle Region)

Produktnummer ABIN2786406

Produktdetails anti-HIPK1 Antikörper

Target: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIPK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PLNLSQNQQS SAAPTSQERS SNPAPRRQQA FVAPLSQAPY TFQHGSPLHS

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against HIPK1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIPK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1210 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HIPK1

Target: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Andere Bezeichnung: HIPK1 (HIPK1 Produkte)

Hintergrund: HIPK1 may play a role as a corepressor for homeodomain transcription factors. HIPK1 phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. HIPK1 may be involved in malignant squamous cell tumor formation.The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.
Alias Symbols: KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2
Protein Interaction Partner: FHL3, HIPK1, DDX54, HAX1, NEB, A2M, PRPF40A, UBC, SKIL, PARK7, ATP13A2, RASSF5, SIAH1, UBE2I, GLUL, SNIP1, DAXX, NKX2-5, TP53, RUNX1, HOXD4,
Protein Size: 1210

Molekulargewicht: 131 kDa

Gen-ID: 204851

NCBI Accession: NM_198268, NP_938009

UniProt: Q86Z02