SMG5 Antikörper (N-Term)
Kurzübersicht für SMG5 Antikörper (N-Term) (ABIN2786101)
Target
Alle SMG5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MSQGPPTGES SEPEAKVLHT KRLYRAVVEA VHRLDLILCN KTAYQEVFKP
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SMG5. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMG5
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 1016 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))
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Andere Bezeichnung
- SMG5
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Hintergrund
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SMG5 plays a role in nonsense-mediated mRNA decay. SMG5 does not have RNase activity by itself. SMG5 promotes dephosphorylation of RENT1. SMG5 is necessary for TERT activity.SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM].
Alias Symbols: EST1B, FLJ34864, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5
Protein Interaction Partner: RBM8A, UPF1, PHB, ZWINT, UBC, APP, HDAC8, STUB1, SMG7, SMG6, SMG1, TERT,
Protein Size: 1016 -
Molekulargewicht
- 114 kDa
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Gen-ID
- 23381
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NCBI Accession
- NM_015327, NP_056142
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UniProt
- Q9UPR3
Target
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