CMTR1 Antikörper (C-Term)
Kurzübersicht für CMTR1 Antikörper (C-Term) (ABIN2786076)
Target
Alle CMTR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- FTSJD2 Antibody - C-terminal region
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Sequenz
- YRLEEMEKIF VRLEMKIIKG SSGTPKLSYT GRDDRHFVPM GLYIVRTVNE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against FTSJD2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human FTSJD2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55152-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CMTR1 (Cap Methyltransferase 1 (CMTR1))
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Andere Bezeichnung
- FTSJD2
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Hintergrund
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Background Information: FTSJD2 is a S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. It methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA to produce m7GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. It may be involved in the interferon response pathway.
Gene Name: FtsJ methyltransferase domain containing 2
Alternative Symbols: MTr1, hMTr1, FTSJD2, KIAA0082
Protein Name: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
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Molekulargewicht
- 95kDa
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Gen-ID
- 23070
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NCBI Accession
- NP_055865
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UniProt
- Q8N1G2
Target
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