FAM120A Antikörper (Middle Region)

Produktnummer ABIN2786049

Der Kaninchen Polyklonal Anti-FAM120A Antikörper wurde für WB validiert. Er ist geeignet, FAM120A in Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd und Schwein zu detektieren.

Kurzübersicht für FAM120A Antikörper (Middle Region) (ABIN2786049)

Target: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM120A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FAM120A Antikörper

Bindungsspezifität: Middle Region

Sequenz: SGGATNHISG NKIGWEKTGS HSEPQARGDP GDQTKAEGSS TASSGSQLAE

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 92%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FAM120A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM120A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1118 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FAM120A

Target: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Andere Bezeichnung: FAM120A

Hintergrund: FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Alias Symbols: C9orf10, DNAPTP1, DNAPTP5, MGC111527, MGC133257, OSSA
Protein Interaction Partner: SPRTN, CEP250, SUMO2, STAU1, UBC, PASK, SUMO1, NEDD8, RNF2, EZH2, BMI1, HECW2, TARDBP, CFTR, GRK5, CAND1, CUL3, SIRT7, Ybx1,
Protein Size: 1118

Molekulargewicht: 122 kDa

Gen-ID: 23196

NCBI Accession: NM_014612, NP_055427

UniProt: Q9NZB2